Bloodstream and C. difficile infections, England
Cases of E. coli, MSSA and MRSA bloodstream infection and of C. difficile infection reported in England each financial year, with UKHSA's rate per 100,000 people, from its mandatory surveillance.
E. coli bloodstream infections
44,879
2025/26 · 13,948 MSSA and 1,144 MRSA bloodstream infections and 17,114 C. difficile infections
Verified against source, 9 November 2026, 15:09 UTC- E. coli bloodstream infections
- MSSA bloodstream infections
- MRSA bloodstream infections
- C. difficile infections
Source: UK Health Security Agency. Contains public sector information licensed under the Open Government Licence v3.0.
Data table
19 periods, newest first
| Period | E. coli bloodstream infections | MSSA bloodstream infections | MRSA bloodstream infections | C. difficile infections |
|---|---|---|---|---|
| 2025/26 | 44,879 | 13,948 | 1,144 | 17,114 |
| 2024/25 | 43,645 | 13,796 | 1,064 | 18,970 |
| 2023/24 | 42,246 | 13,491 | 910 | 16,838 |
| 2022/23 | 38,789 | 13,140 | 787 | 15,563 |
| 2021/22 | 38,050 | 12,312 | 675 | 14,277 |
| 2020/21 | 36,825 | 11,719 | 697 | 12,503 |
| 2019/20 | 43,410 | 12,252 | 815 | 13,213 |
| 2018/19 | 43,290 | 12,106 | 807 | 12,273 |
| 2017/18 | 41,152 | 11,959 | 850 | 13,296 |
| 2016/17 | 40,690 | 11,501 | 825 | 12,848 |
| 2015/16 | 38,315 | 10,610 | 823 | 14,143 |
| 2014/15 | 35,823 | 9,865 | 800 | 14,193 |
| 2013/14 | 34,286 | 9,290 | 862 | 13,362 |
| 2012/13 | 32,309 | 8,812 | 924 | 14,694 |
| 2011/12 | – | 8,767 | 1,116 | 18,022 |
| 2010/11 | – | – | 1,481 | 21,707 |
| 2009/10 | – | – | 1,898 | 25,604 |
| 2008/09 | – | – | 2,935 | 36,095 |
| 2007/08 | – | – | 4,451 | 55,498 |
Source and licence
- Publisher
- UK Health Security Agency
- Check it yourself
- https://www.gov.uk/government/collections/gram-negative-mrsa-and-mssa-bacteraemia-and-c-difficile-infections-annual-epidemiological-commentaries
- Licence
- Open Government Licence v3.0 – Contains public sector information licensed under the Open Government Licence v3.0.
- Retrieved
- 9 November 2026, 14:55 UTC
- Raw files fetched
- https://www.gov.uk/api/content/government/statistics/gram-negative-mrsa-and-mssa-bacteraemia-and-c-difficile-infections-annual-epidemiological-commentary-2025-to-2026SHA-256 4573250e2c2dff00d44e74fa33e90365f7c688cdbabaa1a8dc6d499b9439f225 · 3,994 bytes
- https://assets.publishing.service.gov.uk/media/6aad1933ce3f006bd4346ca2/HCAI-AEC-data-tables-2025-2026.odsSHA-256 94e8586eaed9880de99173b00ca405e1a3d7d17cf03b03d23847f035c370dd8d · 420,753 bytes
Verification
Verified against source, 9 November 2026, 15:09 UTC Run at 9 November 2026, 15:09 UTC; 76 of 76 figures matched the live source.
| Result | Check | Detail |
|---|---|---|
| Pass | Provenance recorded | UK Health Security Agency; Open Government Licence v3.0; retrieved 2026-11-09T14:55:02Z; 2 raw file(s) |
| Pass | Raw files match recorded SHA-256 | 2 of 2 files intact |
| Pass | Re-parsing raw files reproduces figures | 76 of 76 figures and the headline reproduced; the meta's accreditation and rates match |
| Pass | Figures are finite numbers | 76 figures, 0 invalid |
| Pass | Live source matches every figure | 76 of 76 figures match exactly after downloading 2 source file(s) again (2 byte-identical); the headline matches; the meta's accreditation and rates match |
| Pass | GOV.UK table is current | latest period 2025/26 ended 223 days before retrieval (limit 560), from Accompanying data for Gram-negative, MRSA and MSSA bacteraemia and C. difficile infections, up to and including financial year 2025 to 2026 |
| Pass | Table S3 gives Table S1's cases | 56 of 56 figures match Table S3 of the stored tables |
| Pass | UKHSA's main points agree | 4 of 4 figures the main points https://www.gov.uk/government/statistics/gram-negative-mrsa-and-mssa-bacteraemia-and-c-difficile-infections-annual-epidemiological-commentary-2025-to-2026/main-points-for-annual-epidemiological-commentary-gram-negative-mrsa-and-mssa-bacteraemia-and-c-difficile-infections states match, each rounded half up as it rounds them |
| Pass | UKHSA's main points give the rates | 4 of 4 rates per 100,000 people the main points state for 2025/26 match the meta's, each rounded half up to one place |
| Pass | Community-onset and hospital-onset cases make up all cases | 66 of 66 cases of Table S1's years give community-onset and hospital-onset cases that add up to all reported cases, where it gives both |
| Pass | Each rate is the cases per 100,000 of Table S1's population | 67 of 67 cases of Table S1's years give a rate that is its cases per 100,000 of its own mid-year population within 0.05 (67 exactly) |
| Pass | Source page answers | https://www.gov.uk/government/collections/gram-negative-mrsa-and-mssa-bacteraemia-and-c-difficile-infections-annual-epidemiological-commentaries – HTTP 200 |
Notes
- Cases of each infection reported to UKHSA's mandatory surveillance in England each financial year, however and wherever they began, with UKHSA's rate per 100,000 people in the record's JSON. UKHSA began counting MRSA and C. difficile earlier than MSSA and E. coli, so their lines start sooner.
- The UK Health Security Agency publishes these as accredited official statistics.